- Coming soon: Reconstruction alignment information.
- Jun 2020: Enabled download of resurrected sequences.
- Jun 2020: ~140 new resurrected proteins added.
- May 2020: Revenant manuscript accepted in the Oxford Database Journal.
- November 2018: Revenant Beta 1 released.
Have Questions?
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For inquiries or more, please email Gustavo Parisi or visit our contact info section:
Citing Revenant:
Revenant: a database of characterized resurrected proteins.
Matias Sebastian Carletti, Alexander Miguel Monzon, Emilio Garcia-Rios, Guillermo Benitez, Layla Hirsh, Maria Silvina Fornasari, Gustavo Parisi, Revenant: a database of resurrected proteins, Database, Volume 2020, 2020, baaa031, https://doi.org/10.1093/database/baaa031
Integrated Resources:
Welcome to Revenant
Revenant contains a hand-curated collection of 211 resurrected proteins where 55 of them have at least one crystallographic structure. It summarizes a total of 89 crystallized structures of resurrected proteins. All entries in Revenant have been annotated with different information such as: the ancestral node used in the reconstruction, methodologies used for sequence estimation, used sequence alignments, ligand characterization, etc. Several resurrected proteins have additionally, biochemical parameters (i. e. Km, kcat) and thermodynamics parameters characterizing their stability. The oldest Revenant entry corresponds to a reconstruction from ~4200 millions years (MY) and the younger to just ~1.7 MY. All the Revenant proteins are extensively linked with other databases such as PDB, UniProt, Gene Ontology, PubMed and NCBI.
Revenant is created and maintained in a joint effort by the Structural Bioinformatics Group - National University of Quilmes (SBG-UNQ) and the Group of Artificial Intelligence - Pontifical Catholic University of Peru (IA-PUCP) Read more.
Download Revenant
Revenant sequences (FASTA): Download | Description ♦ Revenant database information (CSV): Download | Description
